SCHEMBL2068561

SCHEMBL2068561

Cc1ccc(S(=O)(=O)N[C@H](c2ccccc2)[C@@H](NS(=O)(=O)c2ccc(C)cc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
NPSR1 Q6W5P4 4/20 0.59
CA12 O43570 4/20 0.56
CA9 Q16790 4/20 0.56
CA2 P00918 3/20 0.56
CA1 P00915 1/20 0.56
HTT P42858 2/20 0.54
GAA P10253 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
CYP2C19 P33261 1/20 0.53
GFER P55789 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA7 P43166 1/20 0.52
MEN1 O00255 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607797 1.00 ALDH1A1 (0.59) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL2068549 1.00 ALDH1A1 (0.59) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL2067591 1.00 ALDH1A1 (0.59) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL15841545 0.94 ALDH1A1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL2242392 0.94 ALDH1A1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL15841450 0.94 ALDH1A1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL6005934 0.94 NPSR1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL6433794 0.94 NPSR1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL2242382 0.94 ALDH1A1 (0.54) ALDH1A1NPSR1CA12CA9CA2
SCHEMBL811026 0.94 ALDH1A1 (0.54) ALDH1A1NPSR1CA12CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902207-B2 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed
US-20070142639-A1 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142639-A1 Process for production of amines SMS, CCNT1, PEAK1 ALDH1A1 1001/4885NPSR1 1081/4885CA12 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.