Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777265 | 0.86 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL6743518 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL29113953 | 0.82 | CES1 (0.50) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL14590999 | 0.82 | CES1 (0.50) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL5839252 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL10918172 | 0.78 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL20686405 | 0.78 | CA1 (0.59) | CES2CES1LMNANPSR1KMT2A | |
| SCHEMBL20686427 | 0.78 | SRD5A2 (0.53) | ALDH1A1SMN1; SMN2LMNASRD5A2HTT | |
| Hydrochloric Acid SCHEMBL11083905 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL20686416 | 0.75 | CES2 (0.61) | ALDH1A1SMN1; SMN2CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031591-A1 | METHOD FOR PREPARING MULTI-SUBSTITUTED ACRYLIC ACID COMPOUND | CHANG CHUN PLASTICS CO., LTD. (TW) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031591-A1 | METHOD FOR PREPARING MULTI-SUBSTITUTED ACRYLIC ACID COMPOUND | GRIA4, ASNS, GRIA1 | ALDH1A1 821/4885SMN1; SMN2 2838/4885CES2 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.