Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 3/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20691457 | 0.85 | DNPH1 (0.32) | DNPH1 | |
| SCHEMBL20691327 | 0.82 | SLC29A1 (0.31) | DNPH1 | |
| SCHEMBL24680698 | 0.80 | DNPH1 (0.33) | DNPH1 | |
| SCHEMBL25688857 | 0.79 | P2RY12 (0.38) | DNPH1P2RX3P2RX4P2RX2 | |
| SCHEMBL25688845 | 0.75 | P2RY12 (0.36) | DNPH1 | |
| SCHEMBL20691314 | 0.75 | P2RY12 (0.36) | DNPH1 | |
| SCHEMBL22219998 | 0.74 | P2RY12 (0.35) | DNPH1P2RX3P2RX4P2RX2 | |
| SCHEMBL25693011 | 0.73 | P2RY12 (0.34) | DNPH1 | |
| SCHEMBL25688848 | 0.73 | P2RY12 (0.40) | DNPH1P2RX3P2RX4P2RX2 | |
| SCHEMBL24321986 | 0.72 | P2RY12 (0.37) | DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |