Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 3/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20691327 | 0.96 | SLC29A1 (0.31) | DNPH1SLC29A1 | |
| SCHEMBL24680698 | 0.95 | DNPH1 (0.33) | DNPH1SLC29A1 | |
| SCHEMBL20691314 | 0.87 | P2RY12 (0.36) | DNPH1 | |
| SCHEMBL20692012 | 0.85 | DNPH1 (0.32) | DNPH1 | |
| SCHEMBL20692127 | 0.82 | TYMP (0.33) | DNPH1SLC29A1 | |
| SCHEMBL22349173 | 0.82 | TYMP (0.33) | DNPH1SLC29A1 | |
| SCHEMBL25688857 | 0.80 | P2RY12 (0.38) | DNPH1 | |
| SCHEMBL20691946 | 0.79 | P2RY12 (0.34) | DNPH1 | |
| SCHEMBL25688845 | 0.79 | P2RY12 (0.36) | DNPH1 | |
| SCHEMBL25693011 | 0.77 | P2RY12 (0.34) | DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10744150-B2 | Cyclic dinucleotides as anticancer agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190030057-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190030057-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | DPYD, NTPCR, CD38 | DNPH1 2001/4885SLC29A1 537/4885 |
| US-10744150-B2 | Cyclic dinucleotides as anticancer agents | DPYD, NTPCR, CD38 | DNPH1 2001/4885SLC29A1 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.