SCHEMBL20693154

SCHEMBL20693154

C=C(C)C(=O)OCCNC(=O)Oc1ccc(C(=O)Oc2ccc(OC(O)c3ccc(OC(=O)NCCOC(=O)C(=C)C)cc3)c(C)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
MGLL Q99685 2/20 0.36
POLB P06746 3/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
PTGS2 P35354 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 5/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TSHR P16473 1/20 0.31
ELANE P08246 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301277 0.89 MGLL (0.42) MGLLPOLBAPEX1HTTTDP1
SCHEMBL21883938 0.86 MGLL (0.36) SMN1; SMN2MGLLPOLBAPEX1HTT
SCHEMBL18904280 0.79 TDP1 (0.49) SMN1; SMN2POLBAPEX1HTTTDP1
SCHEMBL19824794 0.77 TDP1 (0.43) SMN1; SMN2POLBAPEX1HTTTDP1
SCHEMBL10014319 0.77 MGLL (0.57) SMN1; SMN2MGLLPOLBAPEX1HTT
SCHEMBL16885166 0.77 POLB (0.59) SMN1; SMN2MGLLPOLBAPEX1HTT
SCHEMBL23391384 0.76 SMN1; SMN2 (0.50) SMN1; SMN2MGLLPOLBAPEX1HTT
SCHEMBL15803535 0.76 SMN1; SMN2 (0.50) SMN1; SMN2MGLLPOLBAPEX1HTT
SCHEMBL17301263 0.75 MGLL (0.42) SMN1; SMN2MGLLPOLBMAPTKDM4E
SCHEMBL20195754 0.75 ELANE (0.38) POLBTDP1MAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209688-B2 Reflective layer obtained by immobilizing cholesteric liquid crystalline phase FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
US-20190033634-A1 METHOD FOR PRODUCING REFLECTIVE LAYER AND REFLECTIVE LAYER FUJIFILM CORPORATION (JP) 2019-01-31 US disclosed