Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.52 |
| ▸ | TUBB | P07437 | 4/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20693105 | 0.81 | TUBB1 (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20693269 | 0.81 | CYP19A1 (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20693185 | 0.80 | GAA (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20689896 | 0.78 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20693265 | 0.77 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20689895 | 0.76 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29689431 | 0.75 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20696534 | 0.75 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30833319 | 0.72 | KMT2A (0.51) | GAAMEN1KMT2APOLB | |
| SCHEMBL29689451 | 0.72 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020026-A1 | DIFLUOROMETHOXY SUBSTITUTED DIPHENYLETHANE AND TRANS-STILBENE DERIVATIVES, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华理生物医药股份有限公司 | 2019-01-31 | — | — | WO | disclosed |