Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.66 |
| ▸ | TUBB | P07437 | 4/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.66 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504099 | 0.88 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29689431 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20696534 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30504090 | 0.82 | CYP19A1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4464142 | 0.81 | HTR2A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29689638 | 0.81 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12770648 | 0.81 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9921235 | 0.80 | KDM4E (0.52) | KDM4EATMMEN1KMT2A | |
| SCHEMBL988997 | 0.80 | KDM4E (0.72) | CYP19A1HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL4967750 | 0.79 | CYP19A1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573490-B | Diaryl-2H-aziridine compounds, preparation method and application thereof | 复旦大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-114573490-A | diaryl-2H-aziridines and diaryl aziridines compounds, preparation method and application thereof | 复旦大学 | 2022-06-03 | — | — | CN | disclosed |