Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694230 | 0.93 | SCD (0.48) | SCDGPR119ALDH1A1HTTNOTUM | |
| SCHEMBL20694252 | 0.86 | LMNA (0.49) | SCDALDH1A1HTTLMNAMAPT | |
| SCHEMBL20694168 | 0.86 | ALDH1A1 (0.43) | SCDALDH1A1HTTLMNAMAPT | |
| SCHEMBL20694199 | 0.86 | KCNH2 (0.48) | ALDH1A1HTTLMNAMAPTALOX12 | |
| SCHEMBL20694197 | 0.84 | ALDH1A1 (0.45) | SCDALDH1A1HTTLMNAMAPT | |
| SCHEMBL5864962 | 0.84 | SCD (0.42) | SCDALDH1A1HTTHRH3LMNA | |
| SCHEMBL5864969 | 0.84 | ALDH1A1 (0.43) | SCDALDH1A1HTTHRH3LMNA | |
| SCHEMBL20694187 | 0.82 | ACACB (0.44) | SCDALDH1A1HTTLMNAMAPT | |
| SCHEMBL20694175 | 0.82 | MAPT (0.47) | ALDH1A1HTTHRH4HRH3LMNA | |
| SCHEMBL20694300 | 0.81 | ALDH1A1 (0.42) | SCDGPR119ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019022223-A1 | CYCLIC AMINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | 東レ株式会社 | 2019-01-31 | — | — | WO | disclosed |