Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 14/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 14/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 14/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 14/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091743 | 0.84 | PDK1 (0.69) | MAPTNPSR1PDK1PDK2PDK3 | |
| SCHEMBL6348339 | 0.83 | PDK1 (0.76) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL6348342 | 0.83 | PDK1 (0.76) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL3850312 | 0.83 | CA1 (0.42) | MEN1KMT2AMAPTHSD17B10PDK1 | |
| SCHEMBL8116203 | 0.83 | KMT2A (0.56) | KMT2ANPSR1PDK1PDK2PDK3 | |
| SCHEMBL618106 | 0.83 | PDK1 (0.70) | MEN1KMT2AHSD17B10PDK1PDK2 | |
| SCHEMBL6349847 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7880575 | 0.81 | PDK1 (0.68) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL15072455 | 0.81 | MAPK1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2PDK1 | |
| SCHEMBL6816450 | 0.81 | GAA (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906537-B2 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2011-03-15 | — | — | US | disclosed |
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2006-08-17 | — | — | US | disclosed |
| CN-1761464-A | Substituted p-diaminobenzene derivatives | LUNDBECK & CO AS H (DK) | 2006-04-19 | — | — | CN | disclosed |
| EP-1613303-A1 | SUBSTITUTED P-DIAMINOBENZENE DERIVATIVES | H. Lundbeck A/S (DK) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004082677-A1 | SUBSTITUTED P-DIAMINOBENZENE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | ABCB1, UGT2B7, CYP2D6 | MEN1 1715/4885KMT2A 3706/4885MAPT 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.