Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 10/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091743 | 0.84 | PDK1 (0.69) | ALOX15PDK1PDK2PDK3PDK4 | |
| SCHEMBL618106 | 0.83 | PDK1 (0.70) | KMT2APDK1PDK2PDK3PDK4 | |
| SCHEMBL2069741 | 0.83 | MEN1 (0.55) | KMT2APDK1PDK2PDK3PDK4 | |
| SCHEMBL31548138 | 0.82 | HTT (0.57) | — | |
| SCHEMBL9359721 | 0.82 | HTT (0.57) | — | |
| SCHEMBL9384576 | 0.81 | PDK1 (0.50) | KMT2AALOX15PDK1PDK2PDK3 | |
| SCHEMBL15072455 | 0.81 | MAPK1 (0.55) | KMT2AALOX15PDK1PDK2PDK3 | |
| SCHEMBL7880575 | 0.81 | PDK1 (0.68) | KMT2APDK1PDK2PDK3PDK4 | |
| SCHEMBL9834269 | 0.80 | KMT2A (0.56) | KMT2AALOX15PYGLNPSR1 | |
| SCHEMBL23885419 | 0.79 | CA1 (0.44) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-108276358-B | N-arylamidine substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | 拜尔农作物科学股份公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-3395171-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-10051861-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2018-08-21 | — | — | US | disclosed |
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013092350-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-1047693-A1 | HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999031091-A1 | HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | AFF4, ARSA, AFF1 | KMT2A 2592/4885ALOX15 4726/4885PDK1 4364/4885 |
| US-10051861-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | AFF4, AFF1, ARSA | KMT2A 2636/4885ALOX15 4694/4885PDK1 4371/4885 |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | AFF4, ARSA, AFF1 | KMT2A 2592/4885ALOX15 4726/4885PDK1 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.