SCHEMBL2069754

SCHEMBL2069754

COC(=O)c1cccc(N2CCOC(C(OC)c3sc(-c4ccc(Cl)cc4)nc3C)C2)c1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.55
PPARD Q03181 6/20 0.48
PPARG P37231 2/20 0.48
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2070245 0.86 PPARA (0.59) PPARAPPARDPPARG
SCHEMBL2069610 0.85 PPARA (0.60) PPARAPPARDPPARG
SCHEMBL2071322 0.84 PPARA (0.41) PPARAPPARDPPARGKDM4E
SCHEMBL2069755 0.79 PPARA (0.61) PPARAPPARDPPARG
SCHEMBL2069611 0.79 PPARA (0.86) PPARAPPARDPPARG
SCHEMBL2070602 0.79 PPARA (0.58) PPARAPPARDPPARG
SCHEMBL2070253 0.79 PPARA (0.66) PPARAPPARDPPARG
SCHEMBL2069937 0.79 PPARA (0.66) PPARAPPARDPPARG
SCHEMBL2069137 0.79 PPARA (0.66) PPARAPPARDPPARG
SCHEMBL2069083 0.76 NR1D1 (0.37) PPARAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902367-B2 Cyclic amino benzoic acid derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-10-25 US disclosed
CN-101014595-A Novel cyclic aminobenzoic acid derivative KYORIN SEIYAKU KK (JP) 2007-08-08 CN disclosed
EP-1780210-A1 NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE Kyorin Pharmaceutical Co., Ltd. (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative PPARA, PPARG, PPARD PPARA 1/4885PPARD 3/4885PPARG 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.