Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069251 | 1.00 | KMT2A (0.50) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL28338828 | 0.81 | KMT2A (0.50) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL6961103 | 0.81 | KMT2A (0.50) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL5962399 | 0.75 | CA1 (0.50) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL4266898 | 0.74 | PPARG (0.52) | KMT2AMTNR1AMTNR1BPOLBSMN1; SMN2 | |
| SCHEMBL8327013 | 0.73 | MTNR1A (0.48) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL2069117 | 0.73 | MTNR1A (0.51) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL7617760 | 0.73 | POLB (0.47) | KMT2AMTNR1AMTNR1BPOLBSMN1; SMN2 | |
| SCHEMBL2069498 | 0.73 | MTNR1A (0.51) | KMT2AMTNR1AMTNR1BPOLBCA12 | |
| SCHEMBL22035767 | 0.73 | KMT2A (0.56) | KMT2APOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902381-B2 | Synthesising method and benzoxathiepine intermediates | PIERRE FABRE MEDICAMENT (FR) | 2011-03-08 | — | — | US | disclosed |