SCHEMBL20697882

SCHEMBL20697882

c1ccc2c(c1)-c1ccc(-c3ccc4c5ccccc5c5cc6c7ccccc7c7ccccc7c7ccccc7c6cc5c5ccccc5c4c3)cc1-c1ccccc1-c1cc(-n3c4ccccc4n4c5ccccc5nc34)ccc1-2

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 3/20 0.34
BMX P51813 2/20 0.34
HPGD P15428 4/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.33
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18701283 0.87 RAB9A (0.36) HPGDALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL22662127 0.83 ALDH1A1 (0.40) FLT3BMXHPGDALDH1A1KDM4E
SCHEMBL18701353 0.83 ESR1 (0.34) HPGDALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL22662208 0.82 ESR1 (0.39) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL20697966 0.82 KDM4E (0.35) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL20697965 0.82 KDM4E (0.35) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL22929890 0.81 KDM4E (0.32) FLT3BMXALDH1A1KDM4ETP53
SCHEMBL22662182 0.80 ALDH1A1 (0.40) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL24120818 0.80 ALDH1A1 (0.32) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL20735401 0.79 KDM4E (0.35) FLT3BMXHPGDALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11322691-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-03 US disclosed
US-20190036031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322691-B2 Organic electroluminescent materials and devices CTCF, AZI2, CACNA2D2 FLT3 990/4885BMX 3012/4885HPGD 1815/4885
US-20190036031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CTCF, CACNA2D2, PPA1 FLT3 1330/4885BMX 2523/4885HPGD 2035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.