Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21182369 | 0.82 | HSD11B1 (0.39) | HSD11B1DPP4PTGS1PTGS2PDE2A | |
| SCHEMBL21187498 | 0.82 | HSD11B1 (0.39) | HSD11B1NSD3DPP4PTGS1PTGS2 | |
| SCHEMBL21187455 | 0.77 | HSD11B1 (0.42) | HSD11B1DPP4P2RX7 | |
| SCHEMBL20698166 | 0.77 | HSD11B1 (0.41) | HSD11B1DPP4PTGS1PTGS2PDE2A | |
| SCHEMBL21187471 | 0.75 | HSD11B1 (0.39) | HSD11B1NSD3DPP4PTGS1PTGS2 | |
| SCHEMBL21187446 | 0.75 | HSD11B1 (0.39) | HSD11B1DPP4PTGS1PTGS2PDE2A | |
| SCHEMBL20697995 | 0.75 | HSD11B1 (0.39) | HSD11B1DPP4PTGS1PTGS2PDE2A | |
| SCHEMBL21187456 | 0.75 | MAPK14 (0.36) | HSD11B1DPP4CNR2PTGS1PTGS2 | |
| SCHEMBL21187459 | 0.72 | DPP4 (0.39) | HSD11B1DPP4PDE2APDE10AALDH1A1 | |
| SCHEMBL20698197 | 0.72 | HSD11B1 (0.40) | HSD11B1DPP4PTGS1PTGS2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |