Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697946 | 0.91 | HSD11B1 (0.39) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698027 | 0.90 | DPP4 (0.40) | HSD11B1DPP4PDE2APDE10A | |
| SCHEMBL20697995 | 0.90 | HSD11B1 (0.39) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698295 | 0.90 | HSD11B1 (0.40) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698033 | 0.89 | CRHR1 (0.37) | HSD11B1PDE2APDE10APTGS1PTGS2 | |
| SCHEMBL20680752 | 0.89 | HSD11B1 (0.38) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698296 | 0.89 | HSD11B1 (0.44) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20697929 | 0.88 | HSD11B1 (0.40) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20697928 | 0.86 | HSD11B1 (0.41) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698327 | 0.85 | PDE2A (0.37) | DPP4PDE2APDE10APGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |