Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698020 | 0.88 | HSD11B1 (0.40) | HSD11B1DPP4IGF1RPDE2APDE10A | |
| SCHEMBL20697929 | 0.88 | HSD11B1 (0.40) | HSD11B1DPP4IGF1RPDE2APDE10A | |
| SCHEMBL20698191 | 0.86 | FGFR1 (0.45) | HSD11B1DPP4IGF1RPDE2APDE10A | |
| SCHEMBL20698196 | 0.86 | FGFR1 (0.39) | ARHSD11B1DPP4IGF1RALDH1A1 | |
| SCHEMBL20698160 | 0.83 | HSD11B1 (0.37) | HSD11B1DPP4IGF1RALDH1A1PDE2A | |
| SCHEMBL20698165 | 0.82 | HSD11B1 (0.44) | HSD11B1DPP4IGF1RPDE2APDE10A | |
| SCHEMBL20697956 | 0.81 | HSD11B1 (0.36) | HSD11B1DPP4IGF1R | |
| SCHEMBL20698166 | 0.81 | HSD11B1 (0.41) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20697930 | 0.79 | HSD11B1 (0.41) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20697928 | 0.79 | HSD11B1 (0.41) | HSD11B1DPP4IGF1RPDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |