Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PDE6A | P16499 | 1/20 | 0.33 |
| ▸ | PDE6G | P18545 | 1/20 | 0.33 |
| ▸ | PDE6B | P35913 | 1/20 | 0.33 |
| ▸ | PDE6C | P51160 | 1/20 | 0.33 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698165 | 0.85 | HSD11B1 (0.44) | HSD11B1IGF1RPDE2APDE10APOLB | |
| SCHEMBL20697929 | 0.83 | HSD11B1 (0.40) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20698020 | 0.83 | HSD11B1 (0.40) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20697928 | 0.83 | HSD11B1 (0.41) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20697930 | 0.83 | HSD11B1 (0.41) | HSD11B1PDE2APDE10APDE7APDE6D | |
| SCHEMBL20698191 | 0.82 | FGFR1 (0.45) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20698196 | 0.82 | FGFR1 (0.39) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20698295 | 0.80 | HSD11B1 (0.40) | HSD11B1IGF1RPDE2APDE10APDE7A | |
| SCHEMBL20698166 | 0.80 | HSD11B1 (0.41) | HSD11B1PDE2APDE10APDE7ADPP4 | |
| SCHEMBL20698122 | 0.80 | FGFR1 (0.41) | HSD11B1TP53PDE2APDE10APDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |