SCHEMBL20698264

SCHEMBL20698264

c1ccc2c(c1)ccc1ccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5cc(-c6cccc7c6ccc6ccc(-c8nc(-c9ccc%10c%11ccccc%11c%11ccccc%11c%10c9)nc(-n9c%10ccccc%10c%10ccccc%109)n8)cc67)ccc54)n3)cc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HPRT1 P00492 4/20 0.33
TUBB4A P04350 2/20 0.33
TUBB P07437 2/20 0.33
TUBA3C P0DPH7 2/20 0.33
TUBA1B P68363 2/20 0.33
TUBA4A P68366 2/20 0.33
TUBB4B P68371 2/20 0.33
TUBB3 Q13509 2/20 0.33
TUBB2A Q13885 2/20 0.33
TUBB8 Q3ZCM7 2/20 0.33
TUBA3E Q6PEY2 2/20 0.33
TUBA1A Q71U36 2/20 0.33
TUBA1C Q9BQE3 2/20 0.33
TUBB6 Q9BUF5 2/20 0.33
TUBB2B Q9BVA1 2/20 0.33
TUBB1 Q9H4B7 2/20 0.33
BMX P51813 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18892767 0.95 CYP1A2 (0.35) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL20698103 0.95 ALDH1A1 (0.35) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL17229100 0.90 HPRT1 (0.41) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL17691943 0.86 HPRT1 (0.40) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL20698104 0.86 ALDH1A1 (0.34) CYP1A2CYP2C9CYP2C19TUBB4ATUBB
SCHEMBL17229114 0.86 ALDH1A1 (0.42) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL10059268 0.86 CYP1A2 (0.35) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL23759461 0.85 MAPT (0.40) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL10059100 0.83 CYP1A2 (0.35) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A
SCHEMBL17231571 0.83 KDM4E (0.38) CYP1A2CYP2C9CYP2C19HPRT1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed