SCHEMBL23759461

SCHEMBL23759461

c1ccc(-c2nc(-c3ccc4ccc5c6ccccc6ccc5c4c3)nc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
HPRT1 P00492 3/20 0.39
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP1B1 Q16678 2/20 0.37
HIF1A Q16665 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 1/20 0.36
CYP1A2 P05177 3/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ATM Q13315 2/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229100 0.94 HPRT1 (0.41) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL26010333 0.94 MAPT (0.36) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL12490823 0.91 MEN1 (0.40) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL30022111 0.91 MEN1 (0.40) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL23759546 0.90 ATM (0.45) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL17691943 0.90 HPRT1 (0.40) MAPTLMNAHPRT1ALDH1A1HSD17B10
SCHEMBL26012329 0.90 MEN1 (0.39) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL17229114 0.90 ALDH1A1 (0.42) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL17864111 0.89 ALDH1A1 (0.39) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL26007228 0.89 TUBB4A (0.37) MAPTSMN1; SMN2NPC1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320203-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-05 US disclosed
US-20230320203-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-05 US disclosed
US-20230309387-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-28 US disclosed
US-20230263051-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-17 US disclosed
US-20230263051-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-17 US disclosed
US-20220109110-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-04-07 US disclosed
US-20210257556-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220109110-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, LEF1, TMEM109 MAPT 1941/4885SMN1; SMN2 2191/4885NPC1 1253/4885
US-20230309387-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, L1CAM, OR10J3 MAPT 2312/4885SMN1; SMN2 2091/4885NPC1 2175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.