Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697937 | 0.92 | PDE2A (0.42) | MAPK1HSD11B1HTTFGFR1PDE2A | |
| SCHEMBL20698028 | 0.88 | FGFR1 (0.45) | MAPK1HSD11B1HTTFGFR1LMNA | |
| SCHEMBL20697938 | 0.87 | MAPK1 (0.46) | MAPK1HTTFGFR1LMNAPOLB | |
| SCHEMBL20698165 | 0.86 | HSD11B1 (0.44) | MAPK1HSD11B1HTTFGFR1PDE2A | |
| SCHEMBL20698030 | 0.84 | FGFR1 (0.48) | MAPK1HTTFGFR1PDE2APDE10A | |
| SCHEMBL20698032 | 0.81 | MAPK1 (0.46) | MAPK1HTTFGFR1POLBALDH1A1 | |
| SCHEMBL20698021 | 0.81 | TNF (0.43) | MAPK1HTTFGFR1LMNAPOLB | |
| SCHEMBL20698027 | 0.79 | DPP4 (0.40) | HSD11B1PDE2APDE10ADPP4 | |
| SCHEMBL20697939 | 0.79 | MAPK1 (0.41) | MAPK1HTTFGFR1POLBDPP4 | |
| SCHEMBL20680745 | 0.76 | MAPK1 (0.47) | MAPK1HTTFGFR1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |