Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698012 | 0.81 | FGFR1 (0.37) | FGFR1ALDH1A1 | |
| SCHEMBL963024 | 0.79 | FGFR1 (0.46) | MAPK1HTTPOLBFGFR1KDM4E | |
| SCHEMBL20697938 | 0.78 | MAPK1 (0.46) | MAPK1HTTPOLBFGFR1TDP1 | |
| SCHEMBL20698292 | 0.76 | MAPK1 (0.44) | MAPK1HTTPOLBFGFR1ALDH1A1 | |
| SCHEMBL20698021 | 0.74 | TNF (0.43) | MAPK1HTTPOLBFGFR1KDM4E | |
| SCHEMBL965352 | 0.73 | ALDH1A1 (0.49) | MAPK1HTTFGFR1ALDH1A1GAA | |
| SCHEMBL20697937 | 0.73 | PDE2A (0.42) | MAPK1HTTPOLBFGFR1GAA | |
| SCHEMBL965353 | 0.73 | ALDH1A1 (0.49) | MAPK1HTTFGFR1ALDH1A1GAA | |
| SCHEMBL20698032 | 0.72 | MAPK1 (0.46) | MAPK1HTTPOLBFGFR1KDM4E | |
| SCHEMBL20697939 | 0.72 | MAPK1 (0.41) | MAPK1HTTPOLBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |