Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697928 | 0.92 | HSD11B1 (0.41) | HSD11B1KCNH2FGFR1DPP4P2RX7 | |
| SCHEMBL20698122 | 0.87 | FGFR1 (0.41) | HSD11B1KCNH2FGFR1DPP4P2RX7 | |
| SCHEMBL20697989 | 0.85 | FGFR1 (0.39) | HSD11B1KCNH2FGFR1DPP4PDE2A | |
| SCHEMBL20697952 | 0.85 | FGFR1 (0.39) | HSD11B1KCNH2FGFR1DPP4P2RX7 | |
| SCHEMBL20697996 | 0.83 | HSD11B1 (0.36) | HSD11B1KCNH2DPP4NR3C1LMNA | |
| SCHEMBL20698297 | 0.83 | FGFR1 (0.43) | HSD11B1FGFR1PDE2APDE10A | |
| SCHEMBL20698165 | 0.83 | HSD11B1 (0.44) | HSD11B1KCNH2FGFR1DPP4PDE2A | |
| SCHEMBL20697930 | 0.83 | HSD11B1 (0.41) | HSD11B1KCNH2DPP4P2RX7HCAR1 | |
| SCHEMBL20698203 | 0.83 | FGFR1 (0.35) | KCNH2FGFR1HCAR1 | |
| SCHEMBL20697990 | 0.81 | FGFR1 (0.39) | KCNH2FGFR1TP53PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |