Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697928 | 0.91 | HSD11B1 (0.41) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20698122 | 0.88 | FGFR1 (0.41) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20697989 | 0.86 | FGFR1 (0.39) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20697952 | 0.86 | FGFR1 (0.39) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20680752 | 0.85 | HSD11B1 (0.38) | HSD11B1DPP4PDE2APDE10APDE7A | |
| SCHEMBL20698165 | 0.85 | HSD11B1 (0.44) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20697930 | 0.84 | HSD11B1 (0.41) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20698297 | 0.84 | FGFR1 (0.43) | HSD11B1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698016 | 0.83 | GABRP (0.37) | HSD11B1KCNH2DPP4PDE2APDE10A | |
| SCHEMBL20698308 | 0.83 | HSD11B1 (0.36) | HSD11B1KCNH2DPP4PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |