Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698165 | 0.86 | HSD11B1 (0.44) | HSD11B1PDE2APDE10AGRM2FGFR1 | |
| SCHEMBL20698322 | 0.84 | HSD11B1 (0.40) | HSD11B1GRM2FGFR1KDM4EIGF1R | |
| SCHEMBL20698324 | 0.78 | HSD11B1 (0.40) | HSD11B1PDE2APDE10AGRM2FGFR1 | |
| SCHEMBL20697928 | 0.78 | HSD11B1 (0.41) | HSD11B1PDE2APDE10AFGFR1IGF1R | |
| SCHEMBL20697930 | 0.78 | HSD11B1 (0.41) | HSD11B1PDE2APDE10A | |
| SCHEMBL20698149 | 0.76 | GRM2 (0.41) | HSD11B1GRM2FGFR1KDM4EPOLB | |
| SCHEMBL20697939 | 0.75 | MAPK1 (0.41) | GRM2FGFR1POLBHTT | |
| SCHEMBL20698028 | 0.75 | FGFR1 (0.45) | HSD11B1FGFR1KDM4ELMNATSHR | |
| SCHEMBL20698122 | 0.75 | FGFR1 (0.41) | HSD11B1PDE2APDE10AFGFR1KDM4E | |
| SCHEMBL20698133 | 0.73 | POLB (0.52) | HSD11B1PDE2APDE10APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |