Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698165 | 0.86 | HSD11B1 (0.44) | HSD11B1GRM2FGFR1MAPK1POLB | |
| SCHEMBL20698149 | 0.84 | GRM2 (0.41) | HSD11B1GRM2FGFR1MAPK1MKNK1 | |
| SCHEMBL20697932 | 0.82 | HSD11B1 (0.38) | HSD11B1GRM2FGFR1MAPK1MKNK1 | |
| SCHEMBL20698323 | 0.78 | HSD11B1 (0.43) | HSD11B1GRM2FGFR1POLBPDE2A | |
| SCHEMBL20697930 | 0.78 | HSD11B1 (0.41) | HSD11B1P2RX7PDE2APDE10A | |
| SCHEMBL20697928 | 0.78 | HSD11B1 (0.41) | HSD11B1FGFR1P2RX7PDE2APDE10A | |
| SCHEMBL20698135 | 0.76 | HSD11B1 (0.42) | HSD11B1GRM2FGFR1MAPK1MKNK1 | |
| SCHEMBL21187500 | 0.75 | HSD11B1 (0.43) | HSD11B1GRM2FGFR1KMT2AHTT | |
| SCHEMBL20698028 | 0.75 | FGFR1 (0.45) | HSD11B1FGFR1MAPK1HTT | |
| SCHEMBL20697939 | 0.75 | MAPK1 (0.41) | GRM2FGFR1MAPK1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |