SCHEMBL20698337

SCHEMBL20698337

c1cnc(-c2cc3c4ccccc4c4ccccc4c3cc2-c2ccc3c4cc(-c5ncncn5)ccc4c4ccc(-c5ncncn5)cc4c3c2)nc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33
BRD4 O60885 1/20 0.33
TDO2 P48775 2/20 0.33
CLK4 Q9HAZ1 3/20 0.33
DYRK1A Q13627 2/20 0.33
PIK3CD O00329 1/20 0.32
PIP5K1C O60331 1/20 0.32
PI4KA P42356 1/20 0.32
PIK3CG P48736 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ADRB2 P07550 1/20 0.32
PIK3CA P42336 1/20 0.31
CYP11B1 P15538 1/20 0.31
PIM1 P11309 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
ACVR1 Q04771 2/20 0.31
MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229027 0.87 PARP1 (0.33) TDO2PIK3CDKDM4EPIK3CACYP11B1
SCHEMBL17229032 0.87 PARP1 (0.33) TDO2PIK3CDKDM4EPIK3CACYP11B1
SCHEMBL30340690 0.87 PARP1 (0.33) TDO2PIK3CDKDM4EPIK3CACYP11B1
SCHEMBL17229024 0.87 PARP1 (0.33) TDO2PIK3CDKDM4EPIK3CACYP11B1
SCHEMBL20698524 0.85 TDO2 (0.30) CYP2A6TDO2
SCHEMBL17229023 0.83 CLK4 (0.42) CYP2A6BRD4CLK4DYRK1APIK3CD
SCHEMBL17229022 0.83 CLK4 (0.42) CYP2A6BRD4CLK4DYRK1APIK3CD
SCHEMBL20698477 0.81 TDO2 (0.33) TDO2CLK4KDM4EACVR1MAP4K4
SCHEMBL17229026 0.81 MAP4K4 (0.32) MAP4K4
SCHEMBL13615949 0.78 PARP1 (0.31) TDO2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed