Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014362 | 0.83 | KDM1A (0.32) | KDM1AKCNH2 | |
| SCHEMBL25139013 | 0.83 | KDM1A (0.31) | KDM1AKCNH2 | |
| SCHEMBL20698803 | 0.82 | NLRP3 (0.33) | KDM1AKCNH2 | |
| SCHEMBL22014366 | 0.82 | NLRP3 (0.33) | KDM1AKCNH2 | |
| SCHEMBL22015051 | 0.79 | SLC6A2 (0.31) | — | |
| SCHEMBL23668441 | 0.78 | NLRP3 (0.41) | KDM1A | |
| SCHEMBL29687431 | 0.78 | NLRP3 (0.41) | KDM1A | |
| SCHEMBL25067179 | 0.78 | FASN (0.30) | — | |
| SCHEMBL25139280 | 0.78 | SLC6A2 (0.30) | — | |
| SCHEMBL25067028 | 0.77 | NLRP3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023145-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | IFM Tre, Inc. (US) | 2019-01-31 | — | — | WO | disclosed |