Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25067028 | 0.84 | NLRP3 (0.36) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL22014337 | 0.84 | NLRP3 (0.36) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL25066905 | 0.84 | NLRP3 (0.36) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL25139280 | 0.83 | SLC6A2 (0.30) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL25067179 | 0.83 | FASN (0.30) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL22015611 | 0.82 | NLRP3 (0.36) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL23692130 | 0.81 | ROCK2 (0.33) | SLC6A2SLC6A4NLRP3 | |
| SCHEMBL20698685 | 0.79 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL22014363 | 0.79 | FASN (0.32) | — | |
| SCHEMBL20699083 | 0.79 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |