SCHEMBL20699446

SCHEMBL20699446

CCCCCCCCCCCCCCN(CCCCCCCCCCCC)C(=O)C(N)C(N)C(=O)C(N)CCCNC(=N)N

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.42
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
RRM1 P23921 1/20 0.39
ALB P02768 1/20 0.37
SPHK1 Q9NYA1 3/20 0.34
NOD1 Q9Y239 4/20 0.34
S1PR2 O95136 2/20 0.33
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
S1PR5 Q9H228 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18148989 1.00 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL27908684 0.99 DPP7 (0.41) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL446666 0.99 DPP7 (0.41) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL27686644 0.99 DPP7 (0.41) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL3486209 0.99 DPP7 (0.41) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL25364547 0.94 EPHX2 (0.39) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL3975670 0.94 EPHX2 (0.39) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL30130875 0.94 EPHX2 (0.39) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL3975666 0.94 EPHX2 (0.39) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL403392 0.93 SLC6A5 (0.38) DPP7GNAI3GNAO1GNAI1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105873568-A Means for lung specific delivery 赛伦斯治疗有限公司 2016-08-17 CN claimed
US-20190038557-A1 MEANS FOR LUNG SPECIFIC DELIVERY SILENCE THERAPEUTICS GMBH (DE) 2019-02-07 US disclosed
CN-105873568-A Means for lung specific delivery 赛伦斯治疗有限公司 2016-08-17 CN disclosed
CN-1968714-B Lipid, lipid complex and application thereof SILENCE THERAPEUTICS AG 2013-10-16 CN disclosed
CN-102940891-A Lipids, lipid complexes and use thereof ATUGEN AG 2013-02-27 CN disclosed
CN-1968714-A Lipid, lipid complex and application thereof ATUGEN AG (DE) 2007-05-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038557-A1 MEANS FOR LUNG SPECIFIC DELIVERY SGMS1, SGMS2, DEGS1 DPP7 3363/4885GNAI3 1545/4885GNAO1 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.