Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238405 | 0.84 | POLB (0.64) | THRBALOX12POLBGAAHSD17B10 | |
| SCHEMBL11054600 | 0.81 | HSD17B10 (0.53) | THRBALOX12POLBGAAHSD17B10 | |
| SCHEMBL30464743 | 0.79 | HSD17B10 (0.71) | THRBALOX12POLBGAAHSD17B10 | |
| SCHEMBL4571036 | 0.79 | HSD17B10 (0.71) | THRBALOX12POLBGAAHSD17B10 | |
| SCHEMBL13159633 | 0.78 | POLB (0.45) | THRBALOX12POLBGAAHSD17B10 | |
| SCHEMBL1425158 | 0.75 | P2RY1 (0.59) | — | |
| SCHEMBL18415572 | 0.75 | THRB (0.67) | THRBALOX12POLBGAAKDM4E | |
| SCHEMBL13159623 | 0.74 | IDO1 (0.44) | THRBALOX12POLBGAATSHR | |
| SCHEMBL11741197 | 0.74 | HDAC8 (0.50) | — | |
| SCHEMBL28557887 | 0.74 | ALDH1A1 (0.50) | THRBALOX12POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833493-B2 | Metal catalyst, method of C-N coupling using the same and applications of the same | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2023-12-05 | — | — | US | disclosed |
| US-20220297101-A1 | METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2022-09-22 | — | — | US | disclosed |
| US-11376576-B2 | Metal catalyst, method of C—N coupling using the same and applications of the same | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2022-07-05 | — | — | US | disclosed |
| US-20210129123-A1 | METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2021-05-06 | — | — | US | disclosed |
| US-20190039057-A1 | METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2019-02-07 | — | — | US | disclosed |