Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21115924 | 0.84 | CNR1 (0.50) | TSHRHSD17B10CYP19A1CNR1CNR2 | |
| SCHEMBL29038982 | 0.82 | CYP2A6 (0.50) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL25825947 | 0.79 | LMNA (0.46) | HSD17B10CNR2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9026707 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL2984821 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL15186454 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL22265340 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL1312812 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL9850260 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL6033056 | 0.78 | HSD17B10 (0.89) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2019-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | TSHR 3949/4885HSD17B10 4529/4885CYP2A6 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.