SCHEMBL20706754

SCHEMBL20706754

c1ccc(-c2ccc3sc4ccc(-n5c6ccccc6c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccc8sc9ccccc9c8c7)ccc65)cc4c3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSPO P30536 2/20 0.38
GPR3 P46089 1/20 0.38
PIM3 Q86V86 1/20 0.38
LIMK1 P53667 1/20 0.36
HDAC4 P56524 1/20 0.36
CYP1A2 P05177 1/20 0.35
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
DNM1 Q05193 1/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN12 Q05209 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23556699 1.00 KDM4E (0.41) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL14212276 0.99 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL25941224 0.99 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL21481440 0.99 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL25941731 0.99 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL14649044 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL17166753 0.97 KDM4E (0.39) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL24398147 0.97 KDM4E (0.39) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL17248412 0.97 KDM4E (0.39) KDM4EATML3MBTL1TSPOGPR3
SCHEMBL17166788 0.97 KDM4E (0.39) KDM4EATML3MBTL1TSPOGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US disclosed
US-20190088883-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-03-21 US disclosed
EP-3439058-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 KDM4E 406/4885ATM 4041/4885L3MBTL1 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.