SCHEMBL21481440

SCHEMBL21481440

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccc7sc8ccccc8c7c6)cc5)ccc43)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
TSPO P30536 1/20 0.38
HDAC4 P56524 1/20 0.38
PIM3 Q86V86 1/20 0.37
GPR3 P46089 1/20 0.37
LIMK1 P53667 1/20 0.35
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.34
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
DNM1 Q05193 1/20 0.33
KMT2A Q03164 2/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14212276 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL25941731 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL25941224 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL25672043 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL14649044 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23556699 0.99 KDM4E (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL20706754 0.99 KDM4E (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL16804091 0.97 ATM (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL24677126 0.97 KDM4E (0.42) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21578628 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE PIEZO1, OR10J3, OR51E2 L3MBTL1 1968/4885KDM4E 2904/4885ATM 2334/4885
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF AOX1, ODC1, OTC L3MBTL1 2702/4885KDM4E 4036/4885ATM 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.