Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067651 | 0.91 | DNM1 (0.52) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL27343719 | 0.91 | ALDH1A1 (0.50) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL5948319 | 0.87 | ALDH1A1 (0.45) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL10985715 | 0.86 | DNM1 (0.58) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL5713041 | 0.86 | DNM1 (0.58) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL23131780 | 0.86 | DNM1 (0.50) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL19281687 | 0.86 | DNM1 (0.44) | DNM1ALDH1A1TDP1TSHRHTR2A | |
| SCHEMBL22971927 | 0.85 | DNM1 (0.36) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL5949200 | 0.85 | DNM1 (0.36) | DNM1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL17526972 | 0.85 | DNM1 (0.39) | DNM1ALDH1A1TSHRHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050702-A1 | KDM INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-3438106-A1 | ANTI-VIRAL COMPOUNDS | AbbVie Ireland Unlimited Company (IE) | 2019-02-06 | — | — | EP | disclosed |