Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 4/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412441 | 0.91 | ALOX5AP (0.35) | DDR1ALOX5APFEN1MAPK14KDM4E | |
| SCHEMBL10281005 | 0.87 | ALOX5AP (0.43) | DDR1ALOX5APFEN1MAPK14KDM4E | |
| SCHEMBL15426462 | 0.83 | NPBWR1 (0.38) | DDR1ALOX5APFEN1MAPK14KDM4E | |
| SCHEMBL15427236 | 0.80 | ALOX5AP (0.42) | DDR1ALOX5APFEN1KDM4ENPC1 | |
| SCHEMBL15426441 | 0.80 | ALOX5AP (0.41) | DDR1TNKSPARP1TNKS2ALOX5AP | |
| SCHEMBL25886583 | 0.76 | POLB (0.31) | DDR1MAPK14FGFR2FGFR3POLB | |
| SCHEMBL20936363 | 0.76 | POLB (0.31) | MAPK14KDM4EFGFR2FGFR3ALDH1A1 | |
| SCHEMBL30989615 | 0.76 | POLB (0.31) | DDR1MAPK14FGFR2FGFR3POLB | |
| SCHEMBL10281056 | 0.75 | POLB (0.48) | DDR1ALDH1A1POLB | |
| SCHEMBL20708838 | 0.75 | MPL (0.41) | ALOX5APFEN1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006429-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-02-06 | — | — | EP | disclosed |