Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068479 | 0.84 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL2069381 | 0.83 | PPARA (0.46) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL2822183 | 0.79 | PPARD (0.44) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL12590669 | 0.78 | PPARD (0.77) | PPARDPPARAPPARG | |
| SCHEMBL2822186 | 0.78 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL2167562 | 0.76 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL2070336 | 0.75 | PTGDR2 (0.42) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL2068734 | 0.74 | PPARA (0.40) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL2070877 | 0.74 | PPARA (0.43) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL2068744 | 0.74 | PPARA (0.41) | PPARDPPARAPPARGPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968723-B2 | Compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-06-28 | — | — | US | disclosed |