Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822183 | 0.88 | PPARD (0.44) | PPARDPPARGPPARAEGLN1GRM5 | |
| SCHEMBL2068479 | 0.80 | PPARD (0.66) | PPARDPPARGPPARA | |
| SCHEMBL2070902 | 0.78 | PPARD (0.53) | PPARDPPARGPPARA | |
| SCHEMBL2822197 | 0.76 | GRM5 (0.43) | PPARDPPARGPPARAGRM5HPGD | |
| SCHEMBL2827433 | 0.72 | PPARG (0.38) | PPARDPPARGPPARAEGLN1GRM5 | |
| SCHEMBL12590669 | 0.70 | PPARD (0.77) | PPARDPPARGPPARA | |
| SCHEMBL2822103 | 0.70 | PPARD (0.47) | PPARDPPARGPPARAGRM5 | |
| SCHEMBL5673869 | 0.68 | PPARD (0.47) | PPARDPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL2821758 | 0.67 | ERN1 (0.44) | GRM5L3MBTL1 | |
| SCHEMBL51244 | 0.67 | TP53 (0.54) | HPGDKDM4EESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |