Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068483 | 0.88 | MMP2 (0.41) | PPARAACACBSMN1; SMN2PPARGPPARD | |
| SCHEMBL2068734 | 0.82 | PPARA (0.40) | PPARASMN1; SMN2PPARGPTGDR2PPARD | |
| SCHEMBL2069999 | 0.81 | PPARD (0.51) | PPARASMN1; SMN2PPARGPPARD | |
| SCHEMBL2069218 | 0.81 | PPARA (0.40) | PPARAACACBSMN1; SMN2PPARGPTGDR2 | |
| SCHEMBL2069381 | 0.79 | PPARA (0.46) | PPARASMN1; SMN2PPARGPTGDR2PPARD | |
| SCHEMBL2070336 | 0.79 | PTGDR2 (0.42) | PPARAACACBPPARGPTGDR2PPARD | |
| SCHEMBL2069236 | 0.78 | PPARA (0.50) | PPARASMN1; SMN2PPARGPTGDR2PPARD | |
| SCHEMBL2825595 | 0.77 | P4HB (0.36) | ACACBACHEALDH1A1MAPTKDM4E | |
| SCHEMBL2825593 | 0.77 | ACACB (0.35) | ACACBACHEALDH1A1MAPT | |
| SCHEMBL2068774 | 0.76 | PPARD (0.38) | PPARASMN1; SMN2PPARGPTGDR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968723-B2 | Compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-06-28 | — | — | US | disclosed |