Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | AOC2 | O75106 | 4/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 13/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20104660 | 0.82 | MAOB (0.55) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL16767431 | 0.76 | AOC3 (0.67) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL20783686 | 0.76 | AOC2 (0.54) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL16767432 | 0.76 | AOC3 (0.67) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL21864984 | 0.75 | MAOA (0.50) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL20709044 | 0.75 | MAOB (0.69) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL20005678 | 0.75 | MAOB (0.69) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL1294612 | 0.75 | MAOB (0.69) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL1294618 | 0.75 | MAOB (0.69) | MAOBMAOAAOC2DAOAOC3 | |
| SCHEMBL1294616 | 0.75 | MAOB (0.69) | MAOBMAOAAOC2DAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438087-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-02-06 | — | — | EP | disclosed |