Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044454 | 0.88 | MAPT (0.43) | PDE4DKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18151908 | 0.86 | RARB (0.46) | ALDH1A1RARBLMNA | |
| SCHEMBL20709061 | 0.81 | RXRA (0.35) | PDE4DKDM4EGAATHRATHRB | |
| SCHEMBL18044471 | 0.80 | MAPT (0.44) | PDE4DKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18499051 | 0.80 | MAPT (0.44) | PDE4DKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18151911 | 0.80 | MAPT (0.44) | PDE4DKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18044474 | 0.79 | MAPT (0.43) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL18044486 | 0.79 | MAPT (0.43) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL18499050 | 0.79 | RARB (0.40) | KDM4EALDH1A1RARBLMNAMAPT | |
| SCHEMBL18044460 | 0.79 | RARB (0.40) | KDM4EALDH1A1RARBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-B1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | JENKEM TECH CO LTD TIANJIN (CN) | 2019-02-06 | — | — | EP | disclosed |