Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816927 | 0.92 | THRB (0.42) | THRBAKR1C3MAPTNPC1LMNA | |
| SCHEMBL21336037 | 0.87 | MAPT (0.40) | THRBAKR1C3MAPTNPC1LMNA | |
| SCHEMBL12733726 | 0.86 | THRB (0.44) | THRBAKR1C3MAPTKMT2AHPGD | |
| SCHEMBL15580461 | 0.84 | PDGFRB (0.37) | THRBMAPTTOP2ANPC1LMNA | |
| SCHEMBL816362 | 0.82 | MAPT (0.45) | THRBAKR1C3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL20110406 | 0.80 | MAPT (0.40) | THRBMAPTNPC1LMNANFKB1 | |
| SCHEMBL12604112 | 0.79 | HTT (0.46) | THRBMAPTNPC1LMNANFKB1 | |
| SCHEMBL30599668 | 0.79 | POLB (0.45) | THRBMAPTNPC1LMNANFKB1 | |
| SCHEMBL1951966 | 0.79 | POLB (0.45) | THRBMAPTNPC1LMNANFKB1 | |
| SCHEMBL20110402 | 0.79 | MAPT (0.37) | THRBMAPTNPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438134-B1 | POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT | ADEKA CORP (JP) | 2021-05-05 | — | — | EP | disclosed |
| EP-3438134-A1 | POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT | Adeka Corporation (JP) | 2019-02-06 | — | — | EP | disclosed |