Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604074 | 0.91 | MAPT (0.38) | PDGFRBPDGFRANPC1LMNAPOLB | |
| SCHEMBL20709680 | 0.87 | NPC1 (0.40) | PDGFRBPDGFRANPC1LMNANFKB1 | |
| SCHEMBL816382 | 0.85 | THRA (0.40) | NPC1LMNAPOLBNFKB1NFKB2 | |
| SCHEMBL20709693 | 0.84 | THRB (0.41) | NPC1LMNAPOLBNFKB1NFKB2 | |
| SCHEMBL30599668 | 0.81 | POLB (0.45) | NPC1LMNAPOLBNFKB1NFKB2 | |
| SCHEMBL1951966 | 0.81 | POLB (0.45) | NPC1LMNAPOLBNFKB1NFKB2 | |
| SCHEMBL816053 | 0.79 | MAPT (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL20709646 | 0.79 | THRA (0.39) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL21615737 | 0.78 | HDAC1 (0.39) | NPC1LMNAPOLBNFKB1NFKB2 | |
| SCHEMBL14601542 | 0.78 | MAPT (0.43) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325168-B1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | ADEKA CORP (JP) | 2014-03-19 | — | — | EP | disclosed |