Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | CCND2 | P30279 | 2/20 | 0.43 |
| ▸ | CCND3 | P30281 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20754017 | 0.84 | MAOB (0.43) | CDK4CCND1CCND2CCND3MAOB | |
| SCHEMBL19231457 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| SCHEMBL13322653 | 0.78 | ATM (0.51) | KDM4EALDH1A1MCHR1ATMMAOB | |
| SCHEMBL19212805 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| SCHEMBL19250689 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| SCHEMBL19212713 | 0.76 | CDK4 (0.46) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| SCHEMBL20753952 | 0.73 | BRD4 (0.39) | ALDH1A1ATMHPGD | |
| SCHEMBL13153192 | 0.73 | MAPK14 (0.46) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| SCHEMBL16519372 | 0.72 | CDK4 (0.47) | CDK4CCND1CCND2CCND3MAOB | |
| SCHEMBL13354919 | 0.71 | BRPF1 (0.53) | KDM4EALDH1A1MCHR1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040083-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040083-A1 | ANTIBACTERIAL COMPOUNDS | OXA1L, SYMPK, TBCD | KDM4E 3569/4885ALDH1A1 2206/4885CDK4 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.