Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.63 |
| ▸ | ITGB7 | P26010 | 20/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280373 | 1.00 | ITGA4 (0.63) | ITGA4ITGB7ITGB1 | |
| SCHEMBL6469673 | 1.00 | ITGA4 (0.63) | ITGA4ITGB7ITGB1 | |
| SCHEMBL24946011 | 0.86 | ITGA4 (0.62) | ITGA4ITGB7ITGB1 | |
| SCHEMBL24946010 | 0.86 | ITGA4 (0.62) | ITGA4ITGB7ITGB1 | |
| SCHEMBL6031755 | 0.84 | ITGA4 (0.73) | ITGA4ITGB7ITGB1 | |
| SCHEMBL8281633 | 0.84 | ITGA4 (0.73) | ITGA4ITGB7ITGB1 | |
| SCHEMBL6469692 | 0.82 | ITGA4 (0.84) | ITGA4ITGB7ITGB1 | |
| SCHEMBL8281604 | 0.80 | ITGA4 (0.76) | ITGA4ITGB7ITGB1 | |
| SCHEMBL6029683 | 0.80 | ITGA4 (0.76) | ITGA4ITGB7ITGB1 | |
| SCHEMBL24945838 | 0.79 | ITGA4 (0.66) | ITGA4ITGB7ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562898-B2 | Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity | EA PHARMA CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20190040059-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562898-B2 | Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity | ITGB4, ITGB7, ITGA4 | ITGA4 3/4885ITGB7 2/4885ITGB1 4/4885 |
| US-20190040059-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | ITGB4, ITGB5, ITGA4 | ITGA4 3/4885ITGB7 14/4885ITGB1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.