Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 2/20 | 0.37 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819130 | 0.81 | GAPDH (0.56) | FPR2GAPDHCMKLR1PPARGTRPA1 | |
| SCHEMBL16235732 | 0.81 | GAPDH (0.56) | FPR2GAPDHCMKLR1PPARGTRPA1 | |
| SCHEMBL16235730 | 0.81 | GAPDH (0.56) | FPR2GAPDHCMKLR1PPARGTRPA1 | |
| SCHEMBL13569836 | 0.76 | FPR2 (0.67) | FPR2GAPDHCMKLR1PPARGALDH1A1 | |
| SCHEMBL5868323 | 0.76 | FPR2 (0.49) | FPR2GAPDHCMKLR1PPARGTRPA1 | |
| SCHEMBL12380534 | 0.76 | FPR2 (0.67) | FPR2GAPDHCMKLR1PPARGALDH1A1 | |
| SCHEMBL5868324 | 0.76 | FPR2 (0.49) | FPR2GAPDHCMKLR1PPARGTRPA1 | |
| SCHEMBL3273794 | 0.73 | — | — | |
| SCHEMBL3273792 | 0.73 | — | — | |
| SCHEMBL6239938 | 0.70 | FPR2 (0.36) | FPR2PPARGTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027877-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-02-07 | — | — | WO | disclosed |