Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LGALS8 | O00214 | 5/20 | 0.46 |
| ▸ | FGF1 | P05230 | 1/20 | 0.44 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PYGB | P11216 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750520 | 1.00 | L3MBTL1 (0.50) | L3MBTL1MAPTLGALS8FGF1LGALS9 | |
| SCHEMBL27108717 | 1.00 | L3MBTL1 (0.50) | L3MBTL1MAPTLGALS8FGF1LGALS9 | |
| SCHEMBL7147713 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL22098622 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL7147710 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL23705114 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL19255530 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL7153250 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL7151279 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA | |
| SCHEMBL10260243 | 0.84 | LGALS8 (0.51) | L3MBTL1MAPTLGALS8FGF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200297693-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2020-09-24 | — | — | US | disclosed |
| US-10695319-B2 | Glucose conjugates of triptolide, analogs and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190038596-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190038596-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SLC2A8, SLC2A4, SLC2A1 | L3MBTL1 843/4885MAPT 3103/4885LGALS8 117/4885 |
| US-20200297693-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | SLC2A8, SLC2A4, SLC2A1 | L3MBTL1 843/4885MAPT 3103/4885LGALS8 117/4885 |
| US-10695319-B2 | Glucose conjugates of triptolide, analogs and uses thereof | SLC2A8, SLC2A4, SLC2A1 | L3MBTL1 843/4885MAPT 3103/4885LGALS8 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.