Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705182 | 0.88 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL20713753 | 0.85 | KLKB1 (0.62) | KLKB1 | |
| SCHEMBL20713887 | 0.84 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL20713747 | 0.82 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL20713784 | 0.80 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL20713648 | 0.80 | KLKB1 (0.64) | KLKB1 | |
| SCHEMBL20713763 | 0.80 | KLKB1 (0.64) | KLKB1 | |
| SCHEMBL20713772 | 0.79 | KLKB1 (0.64) | KLKB1 | |
| SCHEMBL20705067 | 0.78 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL20705069 | 0.78 | KLKB1 (0.59) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |