Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13378760 | 0.85 | POLB (0.47) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL207147 | 0.85 | POLB (0.47) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL3655384 | 0.83 | MAPT (0.41) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL8116198 | 0.82 | MAPT (0.60) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL420805 | 0.82 | MAPT (0.60) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL445744 | 0.82 | MAPT (0.60) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL13011266 | 0.75 | GAA (0.47) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL7869426 | 0.75 | MAPT (0.37) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL16232414 | 0.75 | KAT8 (0.58) | MAPTALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL22313966 | 0.72 | MAPT (0.63) | MAPTALDH1A1TDP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926967-B1 | SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2025-10-08 | — | — | EP | disclosed |
| US-9529119-B2 | Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone-hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20160282516-A1 | METHOD FOR FABRICATING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE AND SILICONE-HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-2845708-B1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| EP-2926967-A1 | Silicone hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-1854490-B1 | INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME | HOYA CORP (JP) | 2015-04-01 | — | — | EP | disclosed |
| EP-1810700-B1 | METHOD OF PRODUCING SURFACE-TREATED INTRAOCULAR LENS AND INTRAOCULAR LENS FOR INHIBITING SECONDARY CATARACT | HOYA CORP (JP) | 2015-04-01 | — | — | EP | disclosed |
| EP-2845708-A1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-8088314-B2 | Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract | HOYA CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-7892284-B2 | Intraocular lens and process for producing the same | HOYA CORPORATION (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20100241225-A1 | CURABLE RESIN COMPOSITION FOR INTRAOCULAR LENS, INTRACULAR LENS MATERIAL AND INTRACULAR LENS | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20090024115-A1 | Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract | HOYA Medical Singapore Pte. Ltd. (SG) | 2009-01-22 | — | — | US | disclosed |
| US-20080177384-A1 | Intraocular Lens and Process for Producing the Same | HOYA Medical Singapore Pte. Ltd. (SG) | 2008-07-24 | — | — | US | disclosed |
| EP-1854490-A1 | INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME | Hoya Corporation (JP) | 2007-11-14 | — | — | EP | disclosed |
| EP-1043365-B1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | HOYA HEALTHCARE CORP (JP) | 2006-10-18 | — | — | EP | disclosed |
| EP-1043365-A1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | Hoya Healthcare Corporation (JP) | 2000-10-11 | — | — | EP | disclosed |