SCHEMBL8116198

SCHEMBL8116198

CC1=NN(c2ccccc2)C(=O)/C1=C\c1c(C)nn(-c2ccccc2)c1O

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.60
▸ ALDH1A1 P00352 7/20 0.60
▸ HPGD P15428 3/20 0.57
▸ TDP1 Q9NUW8 3/20 0.57
▸ KDM4E B2RXH2 5/20 0.57
▸ MAPK1 P28482 5/20 0.57
▸ KMT2A Q03164 8/20 0.56
▸ MEN1 O00255 7/20 0.56
▸ GAA P10253 3/20 0.56
▸ POLB P06746 1/20 0.56
▸ CYP2C9 P11712 1/20 0.56
▸ L3MBTL1 Q9Y468 5/20 0.54
▸ PKM P14618 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ LMNA P02545 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ KAT8 Q9H7Z6 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420805 1.00 MAPT (0.60) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL445744 1.00 MAPT (0.60) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL16232414 0.92 KAT8 (0.58) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL12522408 0.89 KAT8 (0.63) MAPTALDH1A1TDP1KDM4EKMT2A
SCHEMBL13092706 0.89 KAT8 (0.63) MAPTALDH1A1TDP1KDM4EKMT2A
SCHEMBL14493700 0.86 KAT8 (0.59) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL22314650 0.86 MAPT (0.63) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL6680163 0.86 KAT8 (0.59) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL22313966 0.86 MAPT (0.63) MAPTALDH1A1HPGDTDP1KDM4E
SCHEMBL22289103 0.86 MAPT (0.63) MAPTALDH1A1HPGDTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330066-A1 Vasodilator and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2023-10-19 — — US disclosed
US-20230330066-A1 Vasodilator and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2023-10-19 — — US disclosed
WO-2021125345-A1 VASODILATOR AND USE THEREOF 株式会社バイオラジカル研究所 2021-06-24 — — WO disclosed
WO-2020158225-A1 ANTIOXIDANT AND USE THEREOF 株式会社バイオラジカル研究所 2020-08-06 — — WO disclosed
US-8288314-B2 Heat-sensitive transfer sheet FUJIFILM CORPORATION (JP) 2012-10-16 — — US disclosed
US-8258079-B2 Heat-sensitive transfer sheet FUJIFILM CORPORATION (JP) 2012-09-04 — — US disclosed
US-8258079-B2 Heat-sensitive transfer sheet FUJIFILM CORPORATION (JP) 2012-09-04 — — US disclosed
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-02-09 — — US disclosed
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-02-09 — — US disclosed
US-8053390-B2 Heat-sensitive transfer sheet FUJIFILM CORPORATION (JP) 2011-11-08 — — US disclosed
US-20100101714-A1 HEAT-SENSITIVE TRANSFER SHEET FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100101714-A1 HEAT-SENSITIVE TRANSFER SHEET FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100084082-A1 HEAT-SENSITIVE TRANSFER SHEET FUJIFILM CORPORATION (JP) 2010-04-08 — — US disclosed
US-20090246423-A1 HEAT-SENSITIVE TRANSFER SHEET FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090207228-A1 METHOD OF FORMING IMAGE BY THERMAL TRANSFER FUJIFILM CORPORATION (JP) 2009-08-20 — — US disclosed
US-20090076199-A1 RED DYE MIXTURE LANXESS DEUTSCHLAND GMBH (DE) 2009-03-19 — — US disclosed
US-20090076199-A1 RED DYE MIXTURE LANXESS DEUTSCHLAND GMBH (DE) 2009-03-19 — — US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 — — US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 — — US disclosed
EP-1002873-A2 Novel assay systems for vanadium bromoperoxidase Ortho-Clinical Diagnostics, Inc. (US) 2000-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330066-A1 Vasodilator and Use Thereof NOX4, NOX1, NOX5 MAPT 4197/4885ALDH1A1 466/4885HPGD 72/4885
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT SNCA, PSEN1, CDR2 MAPT 43/4885ALDH1A1 2810/4885HPGD 3315/4885
US-20090076199-A1 RED DYE MIXTURE LDHA, IK, LDHB MAPT 802/4885ALDH1A1 94/4885HPGD 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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