Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116198 | 1.00 | MAPT (0.60) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL445744 | 1.00 | MAPT (0.60) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL16232414 | 0.92 | KAT8 (0.58) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL12522408 | 0.89 | KAT8 (0.63) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL13092706 | 0.89 | KAT8 (0.63) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL14493700 | 0.86 | KAT8 (0.59) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL22314650 | 0.86 | MAPT (0.63) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL6680163 | 0.86 | KAT8 (0.59) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL22313966 | 0.86 | MAPT (0.63) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL22289103 | 0.86 | MAPT (0.63) | MAPTALDH1A1HPGDTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12569470-B2 | Vasodilator and use thereof | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2026-03-10 | — | — | US | disclosed |
| US-20230330066-A1 | Vasodilator and Use Thereof | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-20220110916-A1 | Antioxidant and Use Thereof | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2022-04-14 | — | — | US | disclosed |
| US-20160376436-A1 | MATERIAL COMPOSITION FOR PRODUCING BEER BOTTLE AND METHOD OF PRODUCING BEER BOTTLE | BEIJING CHAMGO NANO-TECH CO., LTD. (CN) | 2016-12-29 | — | — | US | disclosed |
| US-20140335517-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | RENASCIENCE CO LTD (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20140335517-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | RENASCIENCE CO LTD (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20140335517-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | RENASCIENCE CO LTD (JP) | 2014-11-13 | — | — | US | disclosed |
| US-8809329-B2 | Detection and treatment of schizophrenia | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809329-B2 | Detection and treatment of schizophrenia | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809329-B2 | Detection and treatment of schizophrenia | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20110028470-A1 | Detection and Treatment of Schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028470-A1 | Detection and Treatment of Schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2189537-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-7645882-B2 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-01-12 | — | — | US | disclosed |
| US-7645882-B2 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-01-12 | — | — | US | disclosed |
| US-7645882-B2 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20070123577-A1 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20070123577-A1 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20070123577-A1 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2007-05-31 | — | — | US | disclosed |
| EP-1693369-A1 | PROTEIN MODIFIER PRODUCTION INHIBITOR | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2006-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123577-A1 | Inhibitor of protein modification products formation | SERPINB6, PROC, PLPBP | MAPT 3796/4885ALDH1A1 3582/4885HPGD 699/4885 |
| US-20110028470-A1 | Detection and Treatment of Schizophrenia | GLO1, CBR1, AOX1 | MAPT 4131/4885ALDH1A1 240/4885HPGD 117/4885 |
| US-20230330066-A1 | Vasodilator and Use Thereof | NOX4, NOX1, NOX5 | MAPT 4197/4885ALDH1A1 466/4885HPGD 72/4885 |
| US-12569470-B2 | Vasodilator and use thereof | ROS1, NOX3, ADRB3 | MAPT 4759/4885ALDH1A1 439/4885HPGD 150/4885 |
| US-20220110916-A1 | Antioxidant and Use Thereof | GPX1, GPX4, SOD1 | MAPT 4229/4885ALDH1A1 137/4885HPGD 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.